国家杰出青年基金获得者：谢建华
Name: Jian-Hua Xie
Special Talent: National Science Fund for Distinguished Young Scholars
Subject: Organic chemistry
Address: Institute of Elemento-Organic Chemistry and State Key Lab of Elemento-Organic Chemistry, Nankai University
Telephone: 022-23508049；13820987446
Fax: 022-23506177
E-Mail: jhxie@nankai.edu.cn
Website address: http://zhou.nankai.edu.cn/
Research Interest:
The main emphasis of my research is the discovery and development of new catalytic synthetic methods with particular interest in asymmetric catalysis, the asymmetric total synthesis of various biologically active natural products and structural analogues, as well as the design and synthesis of new highly efficient chiral ligands and catalysts for asymmetric reactions.
History:
EDUCATION
20072008 Postdoctoral Fellow, University of Maryland, USA, (with Prof. Micheal P. Doyle)
2000-2003 Ph.D. (Chemistry), Nankai University, (with Prof. Qi-Lin Zhou)
1994-1997 M.Sc. (Chemistry), Nankai University, (with Prof. Tian-Lin Liu)
1990-1992 B.Sc. (Chemistry), Sichuan Teachers College
ACADEMIC CAREER
2011-present Professor, Nankai University
2006—2011 Associate Professor, Nankai University
2003—2005 Assistance Professor, Nankai University
Honors and Awards:
2013 Tianjin Natural Science Award (The First-Rank)
2013 Award for Outstanding Young Scientists (National Natural Science Foundation of China)
2012 Thieme Chemistry Journals Award
2008 New Century Excellent Talents Project (Ministry of Education, China)
2007 Tianjin Natural Science Award (The First-Rank)
Selected publications:
1) Liu, Chong; Xie, Jian-Hua*; Li, Ya-Li; Chen, Ji-Qaing; Zhou, Qi-Lin*, Asymmetric hydrogenation of ,-disubstituted cycloketones through dynamic kinetic resolution: An efficient construction of chiral diols with three contiguous stereocenters, Angew. Chem. Int. Ed. 2013, 52, 593–596.
2) Yang, Xiao-Hui; Xie, Jian-Hua*; Liu, Wei-Peng; Zhou, Qi-Lin*, Catalytic asymmetric hydrogenation of -ketoesters: Highly efficient approach to chiral 1,5-diols, Angew. Chem. Int. Ed. 2013, 52, 7833–7836.
3) Cheng, Li-Jie; Xie, Jian-Hua*; Chen, Yong; Wang, Li-Xin; Zhou, Qi-Lin*, Enantioselective total synthesis of Δ8-THC and Δ9-THC via catalytic asymmetric hydrogenation and SNAr cyclization, Org. Lett. 2013, 15, 764–767.
4) Xie, Jian-Hua*; Liu, Xiao-Yan; Yang, Xiao-Hui; Xie, Jian-Bo; Wang, Li-Xin; Zhou, Qi-Lin*, Chiral iridium catalysts bearing spiro pyridine-aminophosphine ligands enable highly efficient asymmetric hydrogenation of -aryl--ketoesters, Angew. Chem. Int. Ed. 2012, 51, 201–203.
5) Zhang, Qian-Qian; Xie, Jian-Hua*; Yang, Xiao-Hui; Xie, Jian-Bo; Zhou, Qi-Lin*, Iridium-catalyzed asymmetric hydrogenation of -substituted ,-unsaturated acyclic ketones: Enatioselective total synthesis of (–)-Mesember, Org. Lett. 2012, 14, 6158–6161.
6) Chen, Ji-Qiang; Xie, Jian-Hua*; Bao, Deng-Hui; Liu, Sheng; Zhou, Qi-Lin*, Total synthesis of (–)-Galanthamine and (–)-Lycoramine via catalytic asymmetric hydrogenation and intromolecular reductive Heck cyclization, Org. Lett. 2012, 14, 2714–2717.
7) Xie, Jian-Hua*; Guo, Lu-Chuan; Yang, Xiao-Hui; Wang, Li-Xin; Zhou, Qi-Lin*, Enantioselective synthesis of 2,6-cis-disubstituted tetrahydropyrans via a tandem catalytic asymmetric hydrogenation/oxa-Michael cyclization: An efficient approach to (–)-Centrolobine, Org. Lett. 2012, 14, 4758–4761.
8) Cheng, Li-Jie; Xie, Jian-Hua*; Wang, Li-Xin; Zhou, Qi-Lin*, Enantioselective synthesis of (–)-CP-55940 via ruthenium catalyzed asymmetric hydrogenation, Adv. Synth. Catal. 2012, 354, 1105–1113.
9) Xie, Jian-Hua*; Liu, Xiao-Yan; Xie, Jian-Bo; Wang, Li-Xin; Zhou, Qi-Lin*, An additional coordination group leads to extremely efficient chiral iridium catalysts for asymmetric hydrogenation of ketones, Angew. Chem. Int. Ed. 2011, 50, 7329–7332.
10) Xie, Jian-Bo; Xie, Jian-Hua*; Liu, Xiao-Yan; Kong, Wei-Ling; Li, Sheng; Zhou, Qi-Lin*, Highly enantioselective hydrogenation of -arylmethylene cycloalkanones catalyzed by iridium complexes of chiral spiro aminophosphine ligands, J. Am. Chem. Soc. 2010, 132, 4538–4539.